| FACTORS |
REFERENCE |
MAIN POINTS |
LEVEL OF EVIDENCE |
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Arthritis Rheum. “Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing.” |
- A herniated disk frequently appears in the lower back.
- It is among the largely prevalent reasons of pain in the lower part of the back, and also pain in the leg.
- Genetic, toxic factors, shear stress or mechanical factors are observed to control disc generation.
- Out of 99 variants 12 of them in 25 particular applicant genes gave proof of relationship (P < 0.05) with intensity of disc signal in the lower and/or in the upper lumbar regions.
- Genetic variants account for interindividual dissimilarities in degradation and disc matrix synthesis.
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| Causes of disc herniation |
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- Lifting/carrying and extreme forward bending.
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Occup Environ Med, “Occupational risk factors for symptomatic lumbar disc herniation; a case-control study.” |
- There was a statistically important constructive relationship amid excessive lumbar disc herniation and forward bending.
- There was a statistically noteworthy relationship among lumbar disc herniation and increasing contact to weight lifting or carrying.
- Data was accumulated in a planned individual interview and analysed by means of logistic deterioration to manage for region, age, diseases and nationality that affect the lumbar spine.
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- Hereditary
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Am Fam Physician. “Clinical evaluation and treatment options for herniated lumbar disc.” |
- The incidence of radiculopathy, pain and various symptoms is dependent on the location and quantity of herniation.
- A comprehensive history and cautious bodily assessment, along with if essential by magnetic resonance imaging, can distinguish a herniated lumbar disc from low back strain and other probable reasons of comparable symptoms.
- Deterioration of the intervertebral disc from a mixture of factors can lead to herniation, mainly at the L5-S1 and L4-5 levels.
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- Lumbar load
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Spine (Phila Pa 1976). “Risk factors for lumbar intervertebral disc herniation in Chinese population: a case-control study.” |
- Family history, lumbar load, hard-working, and time urgency are the major risk factors for lumbar disc herniation.
- physical exercises and sleeping on the hard bed might be the protective factors.
- In individual under the age of 30, lumbar load was the second most common risk factor followed by family history that may lead to lumbar disc herniation.
- In individuals of the age group 30-55 years, lumbar load is a significant risk factor that may lead to disc herniation.
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- Hard-working
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Croat Med J. “Case-control study of risk factors for lumbar intervertebral disc herniation in Croatian island populations.” |
- In population of age 40 years or more, intensity of labour along with family history as well as body mass index was the main risk factors for occurrence of disc herniation.
- Experiments showed the maximum odds ratios (OR) for affirmative family history (OR 4.00), strength of physical labour (OR 2.94) and body mass index of 25.7 or more (OR 2.77).
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- BMI over 25.7
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Croat Med J. “Case-control study of risk factors for lumbar intervertebral disc herniation in Croatian island populations.” |
- In population of age 40 years or more, body mass index along with family history as well as intensity of labour was the main risk factors for occurrence of disc herniation.
- Experiments showed the maximum odds ratios (OR) for affirmative family history (OR 4.00), strength of physical labour (OR 2.94) and body mass index of 25.7 or more (OR 2.77).
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- Cumulative physical workload
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BMC Musculoskelet Disord. “Cumulative occupational lumbar load and lumbar disc disease—results of a German multi-center case-control study (EPILIFT).” |
- According to our study, cumulative physical workload is related to lumbar disc diseases among men and women.
- Population control subjects amid 25 and 70 years of age underwent personal interview concerning whole work-related history and on the base of work task-specific additional surveys done by technical experts who using biomechanical model calculations determined situational lumbar weight represented by the compressive force at the lumbosacral disc.
- Odds ratios (OR) and 95% confidence intervals (CI) were calculated independently for women and men by means of unrestricted logistic regression investigation.
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- Night shift works
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Spine (Phila Pa 1976). “Risk factors for lumbar disc degeneration: a 5-year prospective MRI study in asymptomatic individuals.” |
- The results designate that the degree of disc herniation, the deficiency of sports activities, and night shift work are important danger factors for the growth of lumbar disc degeneration and its development.
- Multiple logistic regression analysis demonstrated that the night shift work (OR, 23.01) is important predictor for disc degeneration.
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J Bone Joint Surg Am. “Long-term disability and return to work among patients who have a herniated lumbar disc: the effect of disability compensation.” |
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